The general research focus of Aqlan lab is Applied Organizational Transformation (AOT) with an emphasis on People, Process, Technology, and Data (PPTD). To achieve successful transformation, organizations need to find a balance between the AOT elements. The rapid advancements in technology require organizations to continuously improve their processes and empower their employees. To study AOT, we conduct research in four relevant themes: (1) Simulation – we use simulation (both physical and digital) to integrate people and process. (2) Automation – we use automation to integrate process and technology. (3) Human-Technology Teaming – we study interaction and collaboration between human and technology. (4) Artificial Intelligence – we integrate artificial intelligence and mixed reality to develop sensor-based models for manufacturing and healthcare applications.